Phenotypic Characterization the Townes Sickle Mice
نویسندگان
چکیده
منابع مشابه
Phenotypic characterization of gastric sensory neurons in mice.
Recent studies suggest that the capsaicin receptor [transient receptor potential vanilloid (TRPV)1] may play a role in visceral mechanosensation. To address the potential role of TRPV1 in vagal sensory neurons, we developed a new in vitro technique allowing us to determine TRPV1 expression directly in physiologically characterized gastric sensory neurons. Stomach, esophagus, and intact vagus ne...
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Bielefeldt, Klaus, Fang Zhong, H. Richard Koerber, and Brian M. Davis. Phenotypic characterization of gastric sensory neurons in mice. Am J Physiol Gastrointest Liver Physiol 291: G987–G997, 2006. First published May 25, 2006; doi:10.1152/ajpgi.00080.2006.— Recent studies suggest that the capsaicin receptor [transient receptor potential vanilloid (TRPV)1] may play a role in visceral mechanosens...
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Pain is a hallmark feature of sickle cell anemia (SCA) but management of chronic as well as acute pain remains a major challenge. Mouse models of SCA are essential to examine the mechanisms of pain and develop novel therapeutics. To facilitate this effort, we compared humanized homozygous BERK and Townes sickle mice for the effect of gender and age on pain behaviors. Similar to previously chara...
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ژورنال
عنوان ژورنال: Blood
سال: 2014
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood.v124.21.4916.4916